Incoming materials arriving with certificates of analysis provide supplier claims yet independent verification prevents costly problems from wrong materials, contamination, or falsified documentation entering production. XRF screening provides rapid elemental analysis for RoHS compliance and material verification according to SR 817.023.21 requirements through non-destructive technique enabling 100% screening when required. This approach enables immediate material verification without sample preparation, prevents wrong materials from entering production through rapid pass/fail decisions, and detects contamination invisible to visual inspection including elemental impurities or coating defects. Essential for demonstrating compliance with hazardous substance restrictions limiting lead, cadmium, mercury, and hexavalent chromium, verifying supplier material certificates through independent testing preventing reliance on potentially inaccurate documentation, and investigating discoloration or corrosion issues potentially linked to elemental contamination or incorrect alloy composition. The non-destructive testing preserves materials for use after verification unlike destructive methods consuming samples, enables high-throughput screening processing numerous samples rapidly, and accommodates various sample forms from raw materials to finished components. For medical device manufacturing, XRF screening validates incoming stainless steel grades preventing costly production with wrong alloys, detects coating thickness variations ensuring consistent properties, and identifies elemental contamination sources during root cause investigations. The methodology provides semi-quantitative results adequate for screening with follow-up definitive testing when potential issues arise, reveals unexpected elements suggesting contamination or material substitution, and enables portable analysis testing materials at receiving or on production floor without laboratory delays.